Are commonly used medications associated with an increased risk of cardiac arrest?
A new study from Department of Cardiology at Gentofte Hospital investigates this.
Each year 3500 Danes and 5000 Swedes suffer from out-of-hospital cardiac arrest, only 1 out of 10 survives.
Causes, risk factors and mechanisms of out-of-hospital cardiac arrest remain partly unresolved.
Previous research has found a correlation between treatment with certain types of medication and cardiac arrest, e.g. the so-called QT prolonging drugs.
However, there continues to be many unsettled questions and unknown links between medical treatment and cardiac arrest, which this study aims to further investigate.
The study is performed by using data from the Danish Cardiac Arrest Register, the Danish National Patient Register and the Danish Register of Medical Product Statistics.
Primarily the link between out-of-hospital cardiac arrest and the widely used types of drugs, NSAID (anti-inflammatory drugs) and diuretics, are explored.
Secondly, the connection between death, including out-of-hospital cardiac arrest, and the use of multiple medications, polypharmacy, is studied.