Associated with UCSF since 2026 | Tel. +45 22 91 38 73 | bolette.skjoedt.rafn@regionh.dk
Bolette Skjødt Rafn is a physiotherapist, PhD, senior researcher at Rigshospitalet and associate professor at the University of Copenhagen. Her work lies at the intersection of clinical oncology, rehabilitation, and mental health. She leads PROTECT, a national multicentre trial on the early detection and management of breast cancer-related lymphoedema, and is also the principal investigator of the Vega Trial, which investigates the impact of exercise communities on personal recovery among young adults with severe mental illness.
Her research covers late effects of cancer treatment, lymphedema, rehabilitation, and physical activity using randomised multicentre studies, systematic reviews, qualitative studies, register-based data, clinical measurements, and questionnaire data. In addition, she has contributed to national clinical guidelines on post-operative rehabilitation following breast cancer surgery and on exercise interventions for neuropathic pain in cancer survivors.
Selected publications
- Svendsen L, Jensen S, Hansen S, Sørensen V, Johansen C, Suetta C, Pappot H, Simonsen C, Hermann Tang L, Oksbjerg Dalton S, Ammitzbøll G, Skjødt Rafn B. Change in skeletal muscle mass during systemic cancer treatment: a systematic review and meta-analysis. Acta Oncol 2026;65:493-510. doi: 10.2340/1651-226X.2026.45726.
- Pop PR, Larsen GS, Thomsen MK, Johansen C, Zachariae R, Rafn BS. Colorectal cancer mortality in persons with severe mental illness: a scoping review with meta-analyses of observational studies. Acta Oncol 2025;64:358-373. doi: 10.2340/1651-226X.2025.42260.
- Jensen S, Røder A, Hayes S, Larsen GS, Fode M, Østergren PB, Al-Hamadani MMN, Johansen C, Rafn BS. Comprehensive assessment of lower limb edema and its association with quality of life among men with prostate cancer. Support Care Cancer. 2025;33(7):586. doi: 10.1007/s00520-025-09613-4.
- Rafn BS, Bodilsen A, von Heymann A, Lindberg MJ, Byllov S, Andreasen TG, Johansen C, Christiansen P, Zachariae R. Examining the efficacy of treatments for arm lymphedema in breast cancer survivors: an overview of systematic reviews with meta-analyses. EClinicalMedicine 2023;67:102397. doi: 10.1016/j.eclinm.2023.102397.
- Wong HCY, Wallen MP, Chan AW, Dick N, Bonomo P, Bareham M, Wolf JR, van den Hurk C, Fitch M, Chow E, Chan RJ; MASCC BCRAL Expert Panel and the Oncodermatology and Survivorship Study Groups. Multinational Association of Supportive Care in Cancer (MASCC) clinical practice guidance for the prevention of breast cancer-related arm lymphoedema (BCRAL): international Delphi consensus-based recommendations. EClinicalMedicine 2024;68:102441. doi: 10.1016/j.eclinm.2024.102441.
- Tse SSW, Wong C, Tane K, Kikawa Y, Rafn BS, Chan AW, Lee SF, Kwan JYY, AlKhaifi M, Sheung R, Kwong C, Tse A, Sham K, Ling J, Liu YM, Leung C, Chan F, Tsang S, Wong J, Choy WY, Choy YP, Lai J, Shum T, Chow E, Wong HCY. Prospective surveillance and early intervention to prevent chronic breast cancer-related arm lymphedema-what are the barriers? Ann Palliat Med 2024;13(6):1513-1520. doi: 10.21037/apm-24-93. PMID: 39632817.
- Rafn BS, Andersen MF, Sørensen V, Bjerre ED, Baandrup L, Vernal DL, Mors O, Knop FK, Wolf RT, Tolver A, Firth J, Nøhr N, Skou ST, Ebdrup BH, Midtgaard J. Value of gym-based group exercise versus usual care for young adults receiving antipsychotic medication: study protocol for the multicenter randomized controlled Vega trial. BMC Psychiatry 2023;23(1):634. doi: 10.1186/s12888-023-05086-z.
- Skjødt Rafn B, Jensen S, Bjerre ED, Wittenkamp MC, Benjaminsen K, Christensen LP, Flyger H, Christiansen P, Johansen C. Prospective surveillance for breast cancer-related lymphedema (PROTECT). Acta Oncol 2023;62(7):808-813. doi: 10.1080/0284186X.2023.2197125.
- Johansen C, von Heymann A, Rafn BS, Borgquist S, Christiansen P, Christensen P, Zachariae R, Pappot H, Lassen U. Late effects - the new focus of follow-up. Acta Oncol 2022;61(10):1163-1164. doi: 10.1080/0284186X.2022.2137845.
- Rafn BS, Christensen J, Larsen A, Bloomquist K. Prospective surveillance for breast cancer-related arm lymphedema: a systematic review and meta-analysis. J Clin Oncol 2022;40(9):1009-1026. doi: 10.1200/JCO.21.01681.